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Constitutive activation of integrin αvβthree influences SERT operate within the adult animal, effects that may be recapitulated, or reversed, by pharmacologically focusing on tyrosine kinases in an ex vivo
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Collectively, these details recommend that integrin αvβ3 receptors dynamically control SERT uptake exercise and stage to novel pathways that could be qualified pharmacologically to the amelioration of five-HT-dependent deficits in Grownup animals.
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